5-Iodo-indirubin-3-monoxime [331467-03-9]

MedChem Express

5-Iodo-indirubin-3-monoxime [331467-03-9]

10

331467-03-9

Research Use Only

99.50

C16H10IN3O2

403.17

5-Iodo-indirubin-3-monoxime is a potent GSK-3beta, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively[1].

O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=C(I)C=C4)=O

-20°C,2°C to 8°C

12352200