5-LOX-IN-6

MedChem Express

5-LOX-IN-6 [1159576-98-3]

5

1159576-98-3

Research Use Only

C22H18ClNO3

379.84

5-LOX-IN-6 (compound 11a) is a direct and reversible inhibitor of 5-lipoxygenase (5-LO). 5-LOX-IN-6 inhibits 5-LO activity in human neutrophils and recombinant human 5-LO with IC50 values of 0.23 and 0.086 microM, respectively. 5-LOX-IN-6 prevents leukotriene biosynthesis. 5-LOX-IN-6 can be used for inflammatory and allergic disorders research[1].

O=C(C1=C(CC2=CC(Cl)=CC=C2)NC3=C1C=C(C4=C3C=CC=C4)O)OCC

12352200