5-NIdR [191421-10-0]

MedChem Express

5-NIdR [191421-10-0]

5

191421-10-0

Research Use Only

98.0

C13H14N2O5

278.26

5-NIdR (1-(beta-D-2-Deoxyribofuranosyl)-5-nitroindole), an artificial nucleoside, exhibits the ability to inhibit the replication of DNA lesions generated by Temozolomide (HY-17364). 5-NIdR induces cancer cells apoptosis and arrests cell cycle at G0 phase. 5-NIdR enhances Temozolomide anti-tumor efficacy in murine glioblastoma model[1].

O=[N+](C1=CC(C=CN2[C@@H]3O[C@H](CO)[C@@H](O)C3)=C2C=C1)[O-]

-20°C,2°C to 8°C

12352200