5-(N,N-Hexamethylene)-amiloride
HY-128067
Overview
- SupplierMedChem Express
- Product Name5-(N,N-Hexamethylene)-amiloride [1428-95-1]
- Delivery Days Customer10
- CAS Number1428-95-1
- CertificationResearch Use Only
- Estimated Purity98.47
- Molecular FormulaC12H18ClN7O
- Molecular Weight311.77
- Scientific Description5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na + /H + exchanger inhibitor, which decreases the intracellular pH (pH i ) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC 50 s of 3.91 microM and 1.34 microM, respectively [1] [2] .
- SMILESO=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200