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ProductsBack/5-O-Demethylnobiletin [2174-59-6]

5-O-Demethylnobiletin [2174-59-6]

HY-N1942
MedChem Express
CAS Number2174-59-6
Product group Chemicals
Estimated Purity99.91
Molecular Weight388.37
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Overview

  • Supplier
    MedChem Express
  • Product Name
    5-O-Demethylnobiletin [2174-59-6]
  • Delivery Days Customer
    9
  • CAS Number
    2174-59-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Molecular Formula
    C20H20O8
  • Molecular Weight
    388.37
  • Scientific Description
    5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX (IC50=0.1 microM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 microM[1].
  • SMILES
    O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=C(OC)C(O)=C13
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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