5-O-DMTr-5-iodo-2-dU-3-CED phosphoramidite [178925-48-9]

MedChem Express

5-O-DMTr-5-iodo-2-dU-3-CED phosphoramidite [178925-48-9]

5

178925-48-9

Research Use Only

C39H46IN4O8P

856.68

5-O-DMTr-5-iodo-2-dU-3-CED phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

O=C(N1[C@H](O2)C[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]2COC(C3=CC=C(C=C3)OC)(C4=CC=CC=C4)C5=CC=C(C=C5)OC)NC(C(I)=C1)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352005