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5,6-Benzoflavone [6051-87-2]

5,6-Benzoflavone [6051-87-2]

Research Use Only
TN6694
TargetMol Chemicals
CAS Number6051-87-2
DownloadMSDS
Product group Chemicals
Estimated Purity99.88%
Molecular Weight272.3
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    5,6-Benzoflavone [6051-87-2]
  • Delivery Days Customer
    10
  • CAS Number
    6051-87-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    5,6-Benzoflavone
  • Estimated Purity
    99.88%
  • Molecular Formula
    C19H12O2
  • Molecular Weight
    272.3
  • Scientific Description
    5,6-Benzoflavone (beta-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (beta-Naphthoflavone) possesses anti-inflammatory and antioxidant activities, inhibits LPS-induced inflammation through the AKT/Nrf-2/HO-1-NF-kappaB signaling axis, inhibits TNF-alpha-induced ICAM-1 and VCAM-1 expression, which can be used to study neurodegenerative diseases.
  • Shelf life instruction
    3 years
  • SMILES
    O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • alpha- and beta-Naphthoflavone synergistically attenuate H(2)O(2)-induced neuron SH-SY5Y cell damage. Zhu Y et al., 2017 Mar, Exp Ther Med
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