5,6,7,8-Tetrahydro-8-deazahomofolic acid [111113-75-8]
HY-117247
CAS Number111113-75-8
Product group Chemicals
Molecular Weight458.47
Overview
- SupplierMedChem Express
- Product Name5,6,7,8-Tetrahydro-8-deazahomofolic acid [111113-75-8]
- Delivery Days Customer9
- CAS Number111113-75-8
- CertificationResearch Use Only
- Molecular FormulaC21H26N6O6
- Molecular Weight458.47
- Scientific Description5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor with inhibitory activity against other folate-related enzymes. 5,6,7,8-Tetrahydro-8-deazahomofolic acid showed mild growth inhibition against enterococci, lactic acid bacteria, and L1210 cells in culture. 5,6,7,8-Tetrahydro-8-deazahomofolic acid also showed weak inhibition against thymidylate synthase, dihydrofolate reductase, glycyl-ribonucleoside aminotransferase, and aminoimidazole-carboxyacyl-ribonucleoside aminotransferase. 5,6,7,8-Tetrahydro-8-deazahomofolic acid showed low substrate activity for thymidylate synthase[1].
- SMILESO=C1C2=C(NC(N)=N1)CC[C@@H](N2)CCNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number111113-75-8
Molecular Weight458.47
- SizePrice
Product group Chemicals
5,6,7,8-Tetrahydro-8-deazahomofolic acidORB1702641
Estimated Purity98%
Molecular Weight458.47
- SizePrice