5alpha-Tetrahydrocorticosterone [600-63-5]

MedChem Express

5alpha-Tetrahydrocorticosterone [600-63-5]

999

600-63-5

Research Use Only

C21H34O4

350.49

5alpha-Tetrahydrocorticosterone (5alpha-HB), an endogenous steroid, is a glucocorticoid receptor (GR) agonist and a metabolite of Corticosterone (HY-B1618). 5alpha-Tetrahydrocorticosterone is an effective topical anti-inflammatory agent in vivo. 5alpha-Tetrahydrocorticosterone reduces metabolites that bind to GR-Corticosterone and its 5alpha-reduced metabolites in rat hepatocytes, with a Kd of 268 nM. 5alpha-Tetrahydrocorticosterone can be used for research on inflammatory skin diseases[1].

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