5(S)-HETE lactone [127708-42-3]

TargetMol Chemicals

5(S)-HETE lactone [127708-42-3]

44

127708-42-3

Chemical

Research Use Only

5(S)-HETE lactone

C20H30O2

302.45

5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE. The ability of (+/-)5-HETE lactone to inhibit rat basophilic leukemia cell 5-lipoxygenase (IC50 = 27 microM) may be entirely due to the 5(S) isomer, but the enantiomers have not been tested separately.

3 years

C(=C/C=C\C/C=C\C/C=C\CCCCC)\[C@H]1OC(=O)CCC1

-20°C

12352200