6-Amino-8-trifluoromethylphenanthridine
HY-134561
Overview
- SupplierMedChem Express
- Product Name6-Amino-8-trifluoromethylphenanthridine [651055-83-3]
- Delivery Days Customer5
- CAS Number651055-83-3
- CertificationResearch Use Only
- Molecular FormulaC14H9F3N2
- Molecular Weight262.23
- Scientific Description6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 microM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.
- SMILESNC1=C2C=C(C(F)(F)F)C=CC2=C(C=CC=C3)C3=N1
- UNSPSC12352200