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6-Amino-8-trifluoromethylphenanthridine [651055-83-3]

HY-134561
MedChem Express
CAS Number651055-83-3
Product group Chemicals
Molecular Weight262.23
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Overview

  • Supplier
    MedChem Express
  • Product Name
    6-Amino-8-trifluoromethylphenanthridine [651055-83-3]
  • Delivery Days Customer
    5
  • CAS Number
    651055-83-3
  • Certification
    Research Use Only
  • Hazard Information
    h319,p264-p280-p305+p351+p338
  • Molecular Formula
    C14H9F3N2
  • Molecular Weight
    262.23
  • Scientific Description
    6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine (HY-135189). It inhibits protein folding activity of the ribosome (PFAR) when used at a concentration of 150 microM.2 6A-8tFP directly competes with protein substrates for the ribosomal active site.
  • SMILES
    NC1=C2C=C(C(F)(F)F)C=CC2=C(C=CC=C3)C3=N1
  • UNSPSC
    12352200