6-Bromo-2-naphthol [15231-91-1]

MedChem Express

6-Bromo-2-naphthol [15231-91-1]

5

15231-91-1

Research Use Only

99.75

C10H7BrO

223.069

6-Bromo-2-naphthol is an RTP (real-time polymerase chain reaction) probe that forms a 1:1 or 2:1 complex with beta-cyclodextrin (beta-CD). 6-Bromo-2-naphthol is capable of real-time monitoring of PCR reactions and quantification of specific nucleic acid sequences. RTP probes are a class of small DNA or RNA sequences labeled with fluorescent dyes and quencher molecules, which can be widely used in gene expression analysis, SNP genotyping, and pathogen detection. 6-Bromo-2-naphthol embeds into the cyclodextrin cavity through hydrophobic interactions, inhibits the oxygen quenching effect, and emits a phosphorescent signal at room temperature. 6-Bromo-2-naphthol can also be used as an intermediate for the synthesis of antibacterial azo dyes, and its derivatives show antibacterial activity against Staphylococcus aureus, Escherichia coli and other bacteria[1][2][3].

BrC1=CC=C2C=C(O)C=CC2=C1

-20°C,2°C to 8°C

12352200