6-Chloromelatonin [63762-74-3]

MedChem Express

6-Chloromelatonin [63762-74-3]

10

63762-74-3

Research Use Only

C13H15ClN2O2

266.72

6-Chloromelatonin is a potent melatonin receptor agonist with greater metabolic stability than melatonin. 6-Chloromelatonin compete for [3H]-melatonin and 2-[125I]-iodomelatonin binding to MT1 receptors (pKi=8.9 and 9.1, respectively). 6-Chloromelatonin compete for [3H]-melatonin binding to MT2 receptors (pKi=9.77)[1][2].

CC(NCCC1=CNC2=C1C=C(OC)C(Cl)=C2)=O

12352200