6-Diazo-5-oxo-L-nor-Leucine

MedChem Express

6-Diazo-5-oxo-L-nor-Leucine [157-03-9]

5

157-03-9

Research Use Only

99.98

C6H9N3O3

171.15

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity [1] [2] [3] .

N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O

-20°C

12352200