6-GNTI (dihydrochloride)

MedChem Express

6-GNTI (dihydrochloride) [2410327-94-3]

10

2410327-94-3

Research Use Only

C27H31Cl2N5O3

544.47

6-GNTI dihydrochloride, a kappa-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over beta-arrestin2 recruitment. 6-GNTI 6-GNTI dihydrochloride only activates the Akt pathway in striatal neurons [1] .

O[C@]12[C@](C3=C(C=C4)C[C@H]2N5CC6CC6)(CC5)[C@](OC3=C4O)([H])C(NC7=CC(NC(N)=N)=CC=C87)=C8C1.Cl.Cl

12352200