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6-Hydroxybenzbromarone [152831-00-0]

6-Hydroxybenzbromarone [152831-00-0]

T10182
TargetMol Chemicals
CAS Number152831-00-0
Product group Chemicals
Molecular Weight440.08
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    6-Hydroxybenzbromarone [152831-00-0]
  • Delivery Days Customer
    14
  • CAS Number
    152831-00-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    6-Hydroxybenzbromarone
  • Molecular Formula
    C17H12Br2O4
  • Molecular Weight
    440.08
  • Scientific Description
    6-Hydroxybenzbromarone is the major metabolite of Benzbromarone. 6-Hydroxybenzbromarone is a protein Eyes Absent 3 (EYA3) inhibitor (IC50: 21.5 microM). It is an angiogenic agent, has strong inhibitory effects on cell migration, tubulogenesis, and angiogenic sprouting.
  • Shelf life instruction
    3 years
  • SMILES
    CCc1oc2cc(O)ccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents. Pandey RN et al., 2013, PLoS One
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