6-Methoxyflavanone [3034-04-6]

MedChem Express

6-Methoxyflavanone [3034-04-6]

5

3034-04-6

Research Use Only

98.95

C16H14O3

254.28

6-Methoxyflavanone (6-MeOF) is a flavonoid compound that can cross the blood-brain barrier. 6-Methoxyflavanone is a positive allosteric modulator of GABAA receptors. 6-Methoxyflavanone exhibits positive allosteric regulatory effects on human recombinant alpha1beta2gamma2L and alpha2beta2gamma2L GABAA receptors, and is relatively inactive on the alpha1beta2 GABAA receptor. 6-Methoxyflavanone showes inhibitory behavior towards the activation of bitter receptor hTAS2R39 and hTAS2R14, demonstrating a reversible and non-overcome antagonistic effect. 6-Methoxyflavanone has the effects of anti-anxiety, analgesia and relief of neuropathic pain[1][2][3][4].

O=C1CC(C2=CC=CC=C2)OC3=CC=C(OC)C=C13

2°C to 8°C

12352200