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6-O-desmethyl Donepezil [120013-56-1]

6-O-desmethyl Donepezil [120013-56-1]

T37360
TargetMol Chemicals
CAS Number120013-56-1
Product group Chemicals
Molecular Weight365.47
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    6-O-desmethyl Donepezil [120013-56-1]
  • Delivery Days Customer
    44
  • CAS Number
    120013-56-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    6-O-desmethyl Donepezil
  • Molecular Formula
    C23H27NO3
  • Molecular Weight
    365.47
  • Scientific Description
    6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 microM in HEK293 cells expressing hERG).
  • Shelf life instruction
    3 years
  • SMILES
    O=C1C2=CC(O)=C(OC)C=C2CC1CC3CCN(CC=4C=CC=CC4)CC3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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