6-O-Methylinosine [5746-29-2]

MedChem Express

6-O-Methylinosine [5746-29-2]

10

5746-29-2

Research Use Only

C11H14N4O5

282.25

6-O-Methylinosine is a hypoxanthine analogue. Hypoxanthine is a kind of purine base mainly present in muscle tissue. And it is a metabolite produced by purine oxidase acting on xanthine. Hypoxanthine has typical anti-inflammatory effects and is a potential endogenous poly(ADP-ribose) polymerase (PARP) inhibitor. It is cytoprotective by inhibiting PAPR activity, inhibiting peroxynitrite-induced mitochondrial depolarization and secondary superoxide production. Hypoxanthine can also be used as an indicator of hypoxia[1][2].

O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(OC)=NC=N3)O[C@@H]1CO

41115811