6,7,4-Trihydroxyflavanone [189689-31-4]

MedChem Express

6,7,4-Trihydroxyflavanone [189689-31-4]

9

189689-31-4

Research Use Only

C15H12O5

272.25

6,7,4-Trihydroxyflavanone is a compound with multiple pharmacological activities, including anti-rheumatic, anti-ischemic, anti-inflammatory, anti-osteoclastogenic and protective T-cells from METH-induced deactivation. 6,7,4-Trihydroxyflavanone has shown potential protective effects in neurotoxicity studies and can be used to inhibit patients with neurodegenerative diseases caused by METH. 6,7,4-Trihydroxyflavanone inhibits METH-induced neurotoxicity by upregulating the Nrf2/HO-1 and PI3K/Akt/mTOR signaling pathways. 6,7,4-Trihydroxyflavanone can also induce Nrf2 nuclear translocation and HO-1 expression, further enhancing its protective effect on neuronal cells[1].

O=C1C2=CC(O)=C(O)C=C2O[C@H](C3=CC=C(C=C3)O)C1

12352200