(6R)-ML753286

MedChem Express

(6R)-ML753286

10

Research Use Only

98.0

C20H25N3O3

355.43

(6R)-ML753286 is an isomer of ML753286 (HY-116494). ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 microM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species[1].

COC1=CC=C2C(NC3=C2C[C@]4(N([C@@H]3CC(C)C)C([C@@H](NC4=O)C)=O)[H])=C1

-20°C,2°C to 8°C

12352200