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Chemical Structure
Chemical Structure
Chemical Structure

7-Azido-4-methylcoumarin [95633-27-5]

Research Use Only
CDX-A0069
Chemodex
CAS Number95633-27-5
Product group Chemicals
Estimated Purity>98%
Molecular Weight201.18
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Overview

  • Supplier
    Chemodex
  • Product Name
    7-Azido-4-methylcoumarin [95633-27-5]
  • Delivery Days Customer
    10
  • CAS Number
    95633-27-5
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Warning
  • Molecular Formula
    C10H7N3O2
  • Molecular Weight
    201.18
  • Scientific Description
    7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators. - Chemical. CAS: 95633-27-5. Formula: C10H7N3O2. MW: 201.18. Synthetic 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. The aromatic azide moiety of AzMC is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with lambdaex = 365 nm and lambdaem = 450 nm. It is a photoaffinity labeling probe for the substrate binding site of human sulfotransferase 1A1 (SULT1A1). 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5-phosphate (PLP)-dependent enzymes (e.g. cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine beta-synthase (CBS) inhibitors and activators.
  • SMILES
    CC1=CC(=O)OC2=CC(=CC=C12)N=[N+]=[N-]
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116134

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