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7-Chloro-4-(piperazin-1-yl)quinoline

ORB1909592
Biorbyt
CAS Number837-52-5
Product group Chemicals
Estimated Purity99.52%
Molecular Weight247.72
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Overview

  • Supplier
    Biorbyt
  • Product Name
    7-Chloro-4-(piperazin-1-yl)quinoline [837-52-5]
  • Delivery Days Customer
    10
  • CAS Number
    837-52-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.52%
  • Molecular Formula
    C13H14ClN3
  • Molecular Weight
    247.72
  • Scientific Description
    7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry, exhibiting diverse pharmacological profiles either alone or as a hybrid with other active pharmacophores. It is a potent sirtuin inhibitor, also inhibiting serotonin uptake (IC50 of 50 microM), and demonstrates antimalarial activity on D10 and K1 strains of P. falciparum with IC50 values of 1.18 microM and 0.97 microM, respectively [1].
  • SMILES
    ClC1=CC2=NC=CC(N3CCNCC3)=C2C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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