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7-Chlorokynurenic acid (sodium salt)

HY-100811A
MedChem Express
CAS Number1263094-00-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.79
Molecular Weight245.59
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Overview

  • Supplier
    MedChem Express
  • Product Name
    7-Chlorokynurenic acid (sodium salt) [1263094-00-3]
  • Delivery Days Customer
    9
  • CAS Number
    1263094-00-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.79
  • Molecular Formula
    C10H5ClNNaO3
  • Molecular Weight
    245.59
  • Scientific Description
    7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 microM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 microM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].
  • SMILES
    O=C(C1=NC2=CC(Cl)=CC=C2C(O)=C1)O[Na]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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