7-Ethoxycoumarin

Chemodex

7-Ethoxycoumarin

10

31005-02-4

Research Use Only

>98%

7-Ethoxycoumarin (7-EC) is a naturally occurring derivative of coumarin that is commonly found in numerous plant species. 7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP450) has been used in the functional characterization of various CYPs. It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. Has been used in high-throughput screens in fluorometric p450 activity assays and is metabolized to the fluorescent metabolite 7-Hydroxycoumarin with lambdaex=370nm; lambdaem=450nm. This product can be used as analytical reference compound. - Chemical. CAS: 31005-02-4. Formula: C11H10O3. MW: 190.2. Soluble in ethanol (50 mg/ml) or DMSO (10mg/ml). 7-Ethoxycoumarin (7-EC) is a naturally occurring derivative of coumarin that is commonly found in numerous plant species. 7-Ethoxycoumarin is a substrate for cytochrome P450 (CYP450) has been used in the functional characterization of various CYPs. It undergoes O-deethylation by various CYP isoforms, including CYP1A1, -1A2, and -2B in mice and CYP2E1 in humans. Has been used in high-throughput screens in fluorometric p450 activity assays and is metabolized to the fluorescent metabolite 7-Hydroxycoumarin with lambdaex=370nm; lambdaem=450nm. This product can be used as analytical reference compound.

RT

41116134