7-Hydroxy methotrexate-d3 (ammonium salt)

MedChem Express

7-Hydroxy methotrexate-d3 (ammonium salt)

5

Research Use Only

7-Hydroxy methotrexate-d 3 (ammonium salt) is deuterium labeled 7-Hydroxymethotrexate. 7-Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY-14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis [1] [2] [3] .

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