7-Hydroxycoumarinyl arachidonate [161180-11-6]

MedChem Express

7-Hydroxycoumarinyl arachidonate [161180-11-6]

10

161180-11-6

Research Use Only

55.73 mM

99.19

C29H36O4

448.59

7-Hydroxycoumarinyl arachidonate (7-HCA) is a fluorogenic substrate of cytosolic phospholipase A2 (PLA2). 7-Hydroxycoumarinyl arachidonate is also a fluorogenic substrate for monoacylglycerol lipase (MAGL). MAGL protein catalyzes the hydrolysis of 7-Hydroxycoumarinyl arachidonat to generate Arachidonic acid (AA) and the highly fluorescent 7-hydroxyl coumarin (7-HC; HY-N0573). Release of 7-HC can be measured using a fluorometer[1][2][3].

CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC1=CC=C2C=CC(OC2=C1)=O)=O

-20°C

12352200