7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro guanosine [2389988-55-8]

MedChem Express

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro guanosine [2389988-55-8]

10

2389988-55-8

Research Use Only

C13H14FN5O5

339.28

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 7,8-Dihydro-8-oxo-7-propargyl-3-deoxy-3-fluoro guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

OC[C@@H]1[C@@H](F)[C@@H](O)[C@H](N2C(N(CC#C)C3=C2NC(N)=NC3=O)=O)O1

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