7,8-Dihydro-8-oxo-7-propargyl-3-deoxy guanosine [2389988-54-7]

MedChem Express

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy guanosine [2389988-54-7]

10

2389988-54-7

Research Use Only

C13H15N5O5

321.29

7,8-Dihydro-8-oxo-7-propargyl-3-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 7,8-Dihydro-8-oxo-7-propargyl-3-deoxy guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

OC[C@@H]1C[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N(CC#C)C2=O)O1

41115811