7,8-Dihydro-8-oxo-7-propargyl guanosine

MedChem Express

7,8-Dihydro-8-oxo-7-propargyl guanosine [2763084-98-4]

10

Research Use Only

C13H15N5O6

337.29

7,8-Dihydro-8-oxo-7-propargyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 7,8-Dihydro-8-oxo-7-propargyl guanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N(CC#C)C3=C2N=C(N)NC3=O)=O)O1

41115811