7a-Hydroxyfrullanolide [105578-87-8]

MedChem Express

7a-Hydroxyfrullanolide [105578-87-8]

5

105578-87-8

Research Use Only

C15H20O3

248.32

7a-Hydroxyfrullanolide has anticancer properties. 7a-Hydroxyfrullanolide reduces polymerization of alpha-, beta-tubulin. 7a-Hydroxyfrullanolide preferrs to bind to beta-tubulin over alpha-tubulin. 7a-Hydroxyfrullanolide also triggers DNA damage response arrests cells in the G2/M-phase. 7a-Hydroxyfrullanolide is an eudesmanolide sesquiterpene lactone (SL) and can be isolated from the flowering plants of the Asteraceae family[1].

O[C@]12[C@](OC(C2=C)=O)([H])C3=C(C)CCC[C@@]3(CC1)C

12352200