7alpha-Hydroxy-4-cholesten-3-one-d7 [2260669-17-6]

MedChem Express

7alpha-Hydroxy-4-cholesten-3-one-d7 [2260669-17-6]

10

2260669-17-6

Research Use Only

98.0

C27H37D7O2

407.68

7alpha-Hydroxy-4-cholesten-3-one-d7 is the deuterium labeled 7alpha-Hydroxy-4-cholesten-3-one. 7alpha-Hydroxy-4-cholesten-3-one is an intermediate in synthesis of bile acids from cholesterol. 7alpha-Hydroxy-4-cholesten-3-one is a pregnane X receptor (PXR) agonist. 7alpha-Hydroxy-cholest-4-en-3-one is a biomarker for bile acid loss, irritable bowel syndrome, and other diseases associated with defective bile acid biosynthesis. 7alpha-Hydroxy-cholest-4-en-3-one is the physiological substrate for CYP8B1[1][2].

C[C@H](CCCC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)CC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O

-20°C

12352200