8-Azanebularine [38874-46-3]

MedChem Express

8-Azanebularine [38874-46-3]

10

38874-46-3

Research Use Only

99.33

C9H11N5O4

253.21

8-Azanebularine, a compound with hydrogen in place of the C6 amino group, inhibits the ADAR2 reaction at high concentrations (IC50=15 mM). 8-Azanebularine is incorporated into an RNA structure recognized by human ADAR2 results in high-affinity binding (KD=2 nM). 8-Azanebularine can be used for the research of ADAR-catalyzed RNA-editing reaction[1].

O[C@H]1[C@](O[C@@H]([C@H]1O)CO)([H])N2C3=NC=NC=C3N=N2

-20°C,2°C to 8°C

12352200