8-Br-7-CH-ADPR [1011457-95-6]

TargetMol Chemicals

8-Br-7-CH-ADPR [1011457-95-6]

9

Research Use Only

C16H23BrN4O14P2

637.22

8-Br-7-CH-ADPR (8-Bromo-7-deazaadenosine-5-O-diphosphoribose) serves as a specific antagonist of TRPM2, functioning by binding to the NUDT9 homology domain within the TRPM2 channel, inhibiting its activation, and subsequently regulating the influx of cations through the cell membrane channel. This compound is utilized in research to explore the role of TRPM2 in processes such as cell death, neurodegenerative diseases, myocardial infarction, and diabetes.

BrC=1N(C=2C(C1)=C(N)N=CN2)[C@@H]3O[C@H](COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(=O)O)(=O)O)[C@@H](O)[C@H]3O

-20°C

12352200