8-Hydroxyefavirenz [205754-33-2]
HY-137397
Overview
- SupplierMedChem Express
- Product Name8-Hydroxyefavirenz [205754-33-2]
- Delivery Days Customer10
- CAS Number205754-33-2
- CertificationResearch Use Only
- Estimated Purity98.0
- Molecular FormulaC14H9ClF3NO3
- Molecular Weight331.67
- Scientific Description8-Hydroxyefavirenz (8-OH-EFV) is a primary metabolite of (HY-10572). 8-Hydroxyefavirenz induces apoptosis via a JNK- and BimEL-dependent mechanism in primary human hepatocytes. 8-Hydroxyefavirenz can be used in research of cancer[1]. 8-Hydroxyefavirenz is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C1NC2=C(O)C=C(Cl)C=C2[C@](C(F)(F)F)(C#CC3CC3)O1
- Storage Instruction-20°C
- UNSPSC12131703