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ProductsBack/8-Methoxypsoralen [298-81-7]
Chemical Structure
Chemical Structure
Chemical Structure

8-Methoxypsoralen [298-81-7]

Research Use Only
CDX-M0156
Chemodex
CAS Number298-81-7
DownloadDatasheet
Product group Chemicals
Estimated Purity>95%
Molecular Weight216.19
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Overview

  • Supplier
    Chemodex
  • Product Name
    8-Methoxypsoralen [298-81-7]
  • Delivery Days Customer
    10
  • CAS Number
    298-81-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Danger
  • Molecular Formula
    C12H8O4
  • Molecular Weight
    216.19
  • Scientific Description
    Chemical. CAS: 298-81-7. Formula: C12H8O4. MW: 216.19. Synthetic. Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). Has more potency than 5-MOP, 5-OH-P, DH-8-MOP and psoralen in inhibiting CYP2B1 (cytochrome P-450 2B1). Completely inhibits the metabolism of nicotine in vitro. Inhibits the metabolism of caffeine. Methoxsalen is a drug with photoactivating properties used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to UVA light. Upon photoactivation, ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. - Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). Has more potency than 5-MOP, 5-OH-P, DH-8-MOP and psoralen in inhibiting CYP2B1 (cytochrome P-450 2B1). Completely inhibits the metabolism of nicotine in vitro. Inhibits the metabolism of caffeine. Methoxsalen is a drug with photoactivating properties used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to UVA light. Upon photoactivation, ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms.
  • SMILES
    COC1=C2OC=CC2=CC2=C1OC(=O)C=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200