8-NBD-cGMP [115993-88-9]

MedChem Express

8-NBD-cGMP [115993-88-9]

5

115993-88-9

Research Use Only

C18H18N9O10PS

583.43

8-NBD-cGMP is a fluorescent analog of cyclic guanosine monophosphate and a potent, membrane-permeable, fluorescent activator of cGMP-dependent protein kinase isozymes I alpha and I beta. 8-NBD-cGMP is barely fluorescent in aqueous solution but fluoresces strongly in hydrophobic environments such as hydrophobic protein binding sites[1]

O=C1C(N=C(SCCNC2=CC=C([N+]([O-])=O)C3=NON=C32)N4[C@H]5[C@H](O)[C@H](O6)[C@@H](COP6(O)=O)O5)=C4N=C(N)N1

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