8-pCPT-2-O-Me-cAMP [510774-50-2]
HY-116312
CAS Number510774-50-2
Product group Chemicals
Molecular Weight485.84
Overview
- SupplierMedChem Express
- Product Name8-pCPT-2-O-Me-cAMP [510774-50-2]
- Delivery Days Customer5
- CAS Number510774-50-2
- CertificationResearch Use Only
- Molecular FormulaC17H17ClN5O6PS
- Molecular Weight485.84
- Scientific Description8-pCPT-2-O-Me-cAMP (8-CPT-2-O-Me-cAMP), an analog of cAMP, is an activator of exchange proteins activated by cAMP (Epac). 8-pCPT-2-O-Me-cAMP activates Epac1 (EC50 = 2.2 microM), but not PKA (EC50 >10 microM). 8-pCPT-2-O-Me-cAMP stimulates Epac-mediated Ca2+ release in pancreatic beta-cells in vitro. 8-pCPT-2-O-Me-cAMP is a Rap1 activator. 8-pCPT-2-O-Me-cAMP enhances the retinal pigment epithelium barrier against the pathological choroidal endothelial cell invasion that occurs in macular degeneration[1][2][3].
- SMILESNC1=C2C(N([C@H]3[C@@H]([C@@]4([H])[C@](COP(O)(O4)=O)([H])O3)OC)C(SC5=CC=C(C=C5)Cl)=N2)=NC=N1
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number510774-50-2
Molecular Weight485.84
- SizePrice
Product group Chemicals
8-CPT-2-O-Me-cAMPORB2646236
CAS Number510774-50-2
Estimated Purity98.00%
Molecular Weight485.84
- SizePrice
Product group Chemicals
8-(4-Chlorophenylthio)-2-O-methyladenosine 3,5-cyclic Monophosphate sodium salt [510774-50-2]SC-202028
CAS Number510774-50-2
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