9-AMN

MedChem Express

9-AMN

5

Research Use Only

C23H28N4O7

472.49

9-AMN is the inhibitor for SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro), inhibits its deubiquitination (DUB) activity and protease activity with IC50 of 4.55 microM and 4.15 microM. 9-AMN inhibits the SARS-CoV variants Delta and Omicron replication in Calu-3 cell with IC50 of 1.04 microM and 2.35 microM[1].

O=C1C(C(N)=O)=C(O)[C@@]2(O)C(C3=C(O)C4=C(O)C(N)=CC(N(C)C)=C4C[C@H]3C[C@H]2[C@@H]1N(C)C)=O

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