9(S)-HpOTrE

MedChem Express

9(S)-HpOTrE [111004-08-1]

5

111004-08-1

Research Use Only

C18H30O4

310.43

9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on alpha-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid.The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.

CC/C=C\C/C=C\C=C\[C@@H](OO)CCCCCCCC(O)=O

12352200