9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) [756499-04-4]

TargetMol Chemicals

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) [756499-04-4]

16

Chemical

Research Use Only

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

C18H31NaO2

302.43

9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor alpha (PPARalpha; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARalpha when used at a concentration of 100 microM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-alpha-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-conjugated linoleic acid reduces serum fasting glucose, insulin, and triglyceride levels and decreases white adipose tissue macrophage infiltration inob/obmice. It also increases body weight gain and body fat in weanling mice.4

3 years

[Na].CCCCCC\C=C\C=C/CCCCCCCC(O)=O

-20°C

12352200