A-1155463 [1235034-55-5]

TargetMol Chemicals

A-1155463 [1235034-55-5]

4

1235034-55-5

Chemical

Research Use Only

A-1155463

98%

C35H32FN5O4S2

669.79

A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).

3 years

C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3

-20°C

12352200