A-1210477

MedChem Express

A-1210477 [1668553-26-1]

10

1668553-26-1

Research Use Only

99.86

C46H55N7O7S

850.04

A-1210477 is a potent and selective inhibitor of MCL-1 with a K i of 0.45 nM [1] . A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner [2] .

O=C(C(N1CCN2CCOCC2)=C(CCCOC3=C4C=CC=CC4=CC=C3)C5=C1C(C6=C(COC7=CC=C(N8CCN(S(=O)(N(C)C)=O)CC8)C=C7)N(C)N=C6C)=CC=C5)O

-20°C,2°C to 8°C

12352200