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ProductsBack/A-381393 [726174-00-1]

A-381393 [726174-00-1]

Research Use Only
HY-116941
MedChem Express
CAS Number726174-00-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.92
Molecular Weight320.43
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Overview

  • Supplier
    MedChem Express
  • Product Name
    A-381393 [726174-00-1]
  • Delivery Days Customer
    10
  • CAS Number
    726174-00-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.92
  • Molecular Formula
    C20H24N4
  • Molecular Weight
    320.43
  • Scientific Description
    A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist, with Kis of 1.5, 1.9 and 1.6 nM for human dopamine D4.4, D4.2, and D4.7 receptor, respectively, >2700-fold selectivity over D1, D2, D3 and D5 dopamine receptors. A-381393 shows moderate affinity for 5-HT2A (Ki, 370 nM)[1].
  • SMILES
    CC1=CC=C(C=C1C)N2CCN(CC2)CC3=NC4=CC=CC=C4N3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200