Bio-Connect

A-582941 (dihydrochloride) [848591-90-2]

HY-59201A
MedChem Express
CAS Number848591-90-2
Product group Chemicals
Estimated Purity99.78
Molecular Weight353.29
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Overview

  • Supplier
    MedChem Express
  • Product Name
    A-582941 (dihydrochloride) [848591-90-2]
  • Delivery Days Customer
    5
  • CAS Number
    848591-90-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.78
  • Hazard Information
    h302-h315-h319,p264-p270-p280-p302+p352-p305+p351+p338-p330-p362+p364-p501
  • Molecular Formula
    C17H22Cl2N4
  • Molecular Weight
    353.29
  • Scientific Description
    A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of alpha7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research[1][2].
  • SMILES
    CN1CC(CN(C2=NN=C(C3=CC=CC=C3)C=C2)C4)C4C1.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200