A 65281 [111279-49-3]

MedChem Express

A 65281 [111279-49-3]

5

111279-49-3

Research Use Only

C17H16F2N4O2S

378.40

A 65281 is a potent DNA gyrase inhibitor with an IC50 value of 0.1 microg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC50 value of 8 microg/mL[1].

O=C1NSC(N(C2=C3C=C(C(N4CCNCC4)=C2F)F)C5CC5)=C1C3=O

12352200