A-674563 HCl (552325-73-2(free base)) [2070009-66-2]
T4444
CAS Number2070009-66-2
Product group Chemicals
Estimated Purity99.69%
Molecular Weight394.9
Overview
- SupplierTargetMol Chemicals
- Product NameA-674563 HCl (552325-73-2(free base))
- Delivery Days Customer9
- CAS Number2070009-66-2
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameA-674563 HCl (552325-73-2(free base))
- Estimated Purity99.69%
- Molecular FormulaC22H23ClN4O
- Molecular Weight394.9
- Scientific DescriptionA-674563 is an orally available, ATP-competitive, and reversible inhibitor of Akt (Ki: 11 nM for Akt1) [1]. It exhibits inhibitory activity against PKA and Cdk2 (IC50: 16/46 nM) but is 10- to >1, 800-fold selective for Akt1 versus additional kinases in the CMGC, CAMK, and TK families [1].
- Shelf life instruction3 years
- SMILESCC=1C=2C(=CC=C(C2)C=3C=C(OC[C@H](CC4=CC=CC=C4)N)C=NC3)NN1.Cl
- Storage Instruction-20°C
- UNSPSC12352200
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