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A-769662 [844499-71-4]

HY-50662
MedChem Express
CAS Number844499-71-4
Product group Chemicals
Estimated Purity99.33
Molecular Weight360.39
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Overview

  • Supplier
    MedChem Express
  • Product Name
    A-769662 [844499-71-4]
  • Delivery Days Customer
    10
  • CAS Number
    844499-71-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.33
  • Molecular Formula
    C20H12N2O3S
  • Molecular Weight
    360.39
  • Scientific Description
    A-769662 is a AMP-activated protein kinase (AMPK) activator. A-769662 inhibits the function of the 26S proteasome by an AMPK-independent mechanism and leads to cell cycle arrest. A-769662 directly stimulates partially purified rat liver AMPK (EC50 = 0.8 microM) and inhibits fatty acid synthesis in primary rat hepatocytes (IC50 = 3.2 microM). A-769662 can alleviate the symptoms of metabolic diseases such as type 2 diabetes[1][2][3][4].
  • SMILES
    N#CC1C(C2=C(NC1=O)SC=C2C3=CC=C(C4=CC=CC=C4O)C=C3)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200