A-800141
HY-119062
Molecular Weight442.57
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameA-800141
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC24H30N2O4S
- Molecular Weight442.57
- Scientific DescriptionA-800141 is an orally active and selective MetAP2 inhibitor with an IC50 of 12 nM. A-800141 has weak inhibitory activity for MetAP1 (IC50 : 36 microM). GAPDH can be used as a biomarker to monitor the MetAP2 inhibition of A-800141. A-800141 has antiangiogenic and anticancer activity in a variety of xenograft tumor models[1].
- SMILESO=C(C1=C2CCCCC2=CC=C1NS(=O)(C3=CC=CC=C3/C=C\CN(CC)CC)=O)O
- UNSPSC12352200