A-841720 [869802-58-4]

MedChem Express

A-841720 [869802-58-4]

10

869802-58-4

Research Use Only

98.0

C17H21N5OS

343.45

A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2].

O=C1C2=C(C3=C(N(C)C)C=CN=C3S2)N=CN1N4CCCCCC4

-20°C

12352200